SCHEMBL11890741

SCHEMBL11890741

O=NCCCC1OCCN(c2ccc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)c(F)c2)C1=O

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15475736 0.92 F10 (0.68) F10
SCHEMBL11890751 0.91 F10 (0.66) F10
SCHEMBL11890681 0.87 F10 (0.58) F10
SCHEMBL15475635 0.86 F10 (0.68) F10
SCHEMBL15482067 0.86 F10 (0.60) F10
SCHEMBL15475575 0.82 F10 (0.69) F10
SCHEMBL2188917 0.81 F10 (0.94) F10
SCHEMBL2991837 0.80 F10 (0.76) F10
SCHEMBL78812 0.79 F10 (1.00) F10
SCHEMBL87622 0.79 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012098089-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-07-26 WO disclosed