SCHEMBL15475635

SCHEMBL15475635

C=CCC1OCCN(c2ccc(N3C[C@H](CNC(=O)c4ccc(Cl)s4)OC3=O)c(F)c2)C1=O

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11890685 0.90 F10 (0.69) F10
SCHEMBL15475736 0.90 F10 (0.68) F10
SCHEMBL11890741 0.86 F10 (0.65) F10
SCHEMBL15482067 0.83 F10 (0.60) F10
SCHEMBL2188917 0.83 F10 (0.94) F10
SCHEMBL2994190 0.82 F10 (0.74) F10
SCHEMBL2991837 0.82 F10 (0.76) F10
SCHEMBL11890681 0.81 F10 (0.58) F10
SCHEMBL78812 0.81 F10 (1.00) F10
SCHEMBL87622 0.81 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-20 US disclosed
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140050743-A1 BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS F13B, F11, SERPINC1 F10 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.