Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL11894034 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDNAAAHSP90AA1 | |
| Salicylic Acid SCHEMBL11894182 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDNAAAHSP90AA1 | |
| Cetylpyridinium SCHEMBL667616 | 0.84 | CHRM2 (0.54) | ALDH1A1KDM4EHPGDNAAAHSP90AA1 | |
| Cetylpyridinium SCHEMBL666198 | 0.81 | CHRM2 (0.50) | ALDH1A1KDM4EHPGDNAAAHSP90AA1 | |
| Acetic Acid SCHEMBL27801326 | 0.80 | KMT2A (0.43) | KDM4EHSP90AA1MEN1KMT2AAPAF1 | |
| Acetic Acid SCHEMBL30205024 | 0.80 | KMT2A (0.43) | KDM4EHSP90AA1MEN1KMT2AAPAF1 | |
| Acetic Acid SCHEMBL28714372 | 0.80 | KMT2A (0.43) | KDM4EHSP90AA1MEN1KMT2AAPAF1 | |
| Acetic Acid SCHEMBL28708071 | 0.80 | KMT2A (0.43) | KDM4EHSP90AA1MEN1KMT2AAPAF1 | |
| SCHEMBL1129842 | 0.80 | HSP90AA1 (0.41) | ALDH1A1KDM4EHSP90AA1MEN1KMT2A | |
| Acetic Acid SCHEMBL2062147 | 0.79 | KMT2A (0.41) | KDM4EHSP90AA1MEN1KMT2AAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740543-A1 | INCREASED SATURATION OF ICE MELTING COMPOSITIONS AND METHODS OF USE | BASF SE (DE) | 2020-11-25 | — | — | EP | claimed |
| CN-111511871-A | Enhanced ice melting composition saturation and methods of use | 巴斯夫欧洲公司 | 2020-08-07 | — | — | CN | claimed |
| WO-2019141568-A1 | INCREASED SATURATION OF ICE MELTING COMPOSITIONS AND METHODS OF USE | BASF SE (DE) | 2019-07-25 | — | — | WO | claimed |
| WO-2012105958-A1 | IONIC LIQUID SOLAR PONDS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-08-09 | — | — | WO | claimed |
| US-20120192856-A1 | IONIC LIQUID SOLAR PONDS | H & C SCIENTIFIC RESOURCES INTERNATIONAL LLC | 2012-08-02 | — | — | US | claimed |
| US-11584874-B2 | Increased saturation of ice melting compositions and methods of use | BASF SE (DE) | 2023-02-21 | — | — | US | disclosed |
| EP-3740543-A1 | INCREASED SATURATION OF ICE MELTING COMPOSITIONS AND METHODS OF USE | BASF SE (DE) | 2020-11-25 | — | — | EP | disclosed |
| US-20200339851-A1 | INCREASED SATURATION OF ICE MELTING COMPOSITIONS AND METHODS OF USE | BASF CORPORATION | 2020-10-29 | — | — | US | disclosed |
| CN-111511871-A | Enhanced ice melting composition saturation and methods of use | 巴斯夫欧洲公司 | 2020-08-07 | — | — | CN | disclosed |
| WO-2019141568-A1 | INCREASED SATURATION OF ICE MELTING COMPOSITIONS AND METHODS OF USE | BASF SE (DE) | 2019-07-25 | — | — | WO | disclosed |
| WO-2012105958-A1 | IONIC LIQUID SOLAR PONDS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2012-08-09 | — | — | WO | disclosed |
| US-20120192856-A1 | IONIC LIQUID SOLAR PONDS | H & C SCIENTIFIC RESOURCES INTERNATIONAL LLC | 2012-08-02 | — | — | US | disclosed |