Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894890 | 0.89 | PLA2G2A (0.40) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894630 | 0.85 | GAA (0.55) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894960 | 0.84 | DHODH (0.45) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894698 | 0.84 | KDM4E (0.49) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894797 | 0.83 | DHODH (0.40) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894744 | 0.83 | DHODH (0.40) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11895456 | 0.82 | MEN1 (0.39) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894978 | 0.81 | NOTUM (0.38) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894643 | 0.81 | MEN1 (0.37) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11894650 | 0.81 | DHODH (0.41) | DHODHMEN1KMT2AALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487175-A1 | PHARMACEUTICAL PRODUCT CONTAINING AROMATIC HETEROCYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120196854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196854-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AROMATIC HETEROCYCLIC COMPOUND | CYP2C18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP2B6 | DHODH 1958/4885MEN1 2020/4885KMT2A 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.