Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22294661 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL20847794 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL2564858 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL2564856 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL30883184 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL11896000 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL14925210 | 1.00 | TSHR (0.44) | TSHRHIF1AEPAS1ALDH1A1TDP1 | |
| SCHEMBL514049 | 0.98 | — | — | |
| SCHEMBL514050 | 0.98 | — | — | |
| SCHEMBL514860 | 0.98 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487149-A1 | METHOD FOR PRODUCING KETONE | JX Nippon Oil & Energy Corporation (JP) | 2012-08-15 | — | — | EP | disclosed |
| US-20120197036-A1 | METHOD FOR MANUFACTURING KETONE | OSAKA UNIVERSITY (JP) | 2012-08-02 | — | — | US | disclosed |
| CN-102548942-A | Method for producing ketone | JX NIPPON OIL & ENERGY CORP | 2012-07-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120197036-A1 | METHOD FOR MANUFACTURING KETONE | CBR1, CBR3, DUOX1 | TSHR 2444/4885HIF1A 482/4885EPAS1 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.