Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9277681 | 1.00 | LMNA (0.36) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL3644921 | 1.00 | LMNA (0.36) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL11897987 | 1.00 | LMNA (0.36) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL15146953 | 0.88 | LMNA (0.35) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL30468142 | 0.81 | GLA (0.34) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL24418101 | 0.80 | HPGD (0.34) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL17145146 | 0.80 | HPGD (0.34) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL15144344 | 0.80 | HPGD (0.34) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL13839337 | 0.80 | MEN1 (0.31) | LMNAKMT2AMEN1CYP3A4 | |
| SCHEMBL15136855 | 0.80 | MEN1 (0.31) | LMNAKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193116-B1 | PROCESS FROM SHIKIMIC ACID TO OSELTAMIVIR PHOSPHATE | HOFFMANN LA ROCHE (CH) | 2012-08-08 | — | — | EP | disclosed |