Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926654 | 0.98 | CNR2 (0.38) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11926671 | 0.94 | CNR2 (0.37) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11926656 | 0.91 | CNR2 (0.39) | CNR2ATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL11926751 | 0.91 | CNR2 (0.39) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11926659 | 0.88 | PDK2 (0.37) | CNR2ALDH1A1SMN1; SMN2GLAKDM4E | |
| SCHEMBL11926604 | 0.86 | CNR2 (0.46) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11926754 | 0.85 | POLB (0.35) | CNR2ATMALDH1A1SMN1; SMN2GLA | |
| SCHEMBL11926652 | 0.83 | POLB (0.35) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL11901193 | 0.82 | CNR2 (0.40) | CNR2ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12521380 | 0.81 | KDM4E (0.31) | KDM4EMAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785636-B2 | Substituted indoloacridines for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8785636-B2 | Substituted indoloacridines for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
| WO-2011042107-A2 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, L1CAM, OR10J3 | CNR2 3281/4885ATM 3650/4885TDP1 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.