Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11926654 | 0.93 | CNR2 (0.38) | CNR2KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL11899248 | 0.91 | CNR2 (0.41) | CNR2KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL11926671 | 0.88 | CNR2 (0.37) | CNR2KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL12521350 | 0.85 | KDM4E (0.43) | KDM4EATML3MBTL1ALDH1A1PTGER4 | |
| SCHEMBL12519800 | 0.84 | KDM4E (0.39) | KDM4EATML3MBTL1ALDH1A1DUSP3 | |
| SCHEMBL11926659 | 0.84 | PDK2 (0.37) | CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL12519834 | 0.83 | KDM4E (0.40) | KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL12521362 | 0.82 | KDM4E (0.39) | KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL11926751 | 0.82 | CNR2 (0.39) | CNR2KDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL11926652 | 0.82 | POLB (0.35) | CNR2ATML3MBTL1ALDH1A1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785636-B2 | Substituted indoloacridines for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202997-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, L1CAM, OR10J3 | CNR2 3281/4885KDM4E 3239/4885ATM 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.