Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL27939761 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL182989 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL11235035 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL66252 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL13234423 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL15043 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL195316 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL491341 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL15005463 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 | |
| Methacrylic Acid SCHEMBL2230382 | 0.89 | TDP1 (0.53) | TDP1FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758597-B2 | Reducing polymerization-induced shrinkage stress by reversible addition-fragmentation chain transfer | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-09-12 | — | — | US | disclosed |
| US-8877830-B2 | Stress relief for crosslinked polymers | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2014-11-04 | — | — | US | disclosed |
| US-20130096219-A1 | REDUCING POLYMERIZATION-INDUCED SHRINKAGE STRESS BY REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-04-18 | — | — | US | disclosed |
| US-20120202917-A1 | Stress Relief for Crosslinked Polymers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202917-A1 | Stress Relief for Crosslinked Polymers | DDIT3, ERCC4, ERCC5 | TDP1 849/4885FFAR3 651/4885LCK 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.