Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27093069 | 0.90 | TP53 (0.52) | ESR1ESR2LMNASLC6A2SLC6A3 | |
| SCHEMBL11344794 | 0.86 | ESR1 (0.44) | ESR1ESR2SLC6A2KMT2ACA12 | |
| SCHEMBL5153650 | 0.84 | ESR1 (0.63) | ESR1ESR2LMNASLC6A2SLC6A3 | |
| SCHEMBL1096056 | 0.83 | ESR1 (0.49) | ESR1ESR2LMNASLC6A2SLC6A3 | |
| SCHEMBL28543673 | 0.80 | NPSR1 (0.52) | ESR1ESR2KMT2ATDP1ALDH1A1 | |
| SCHEMBL5337633 | 0.79 | NR4A2 (0.47) | TP53 | |
| SCHEMBL9419435 | 0.79 | ALDH1A1 (0.48) | ESR1ESR2TP53TSHRALDH1A1 | |
| SCHEMBL891147 | 0.78 | ESR1 (0.64) | ESR1ESR2LMNASLC6A2SLC6A3 | |
| SCHEMBL1129618 | 0.78 | ESR1 (0.64) | ESR1ESR2LMNASLC6A2KMT2A | |
| SCHEMBL14996377 | 0.77 | ESR1 (0.62) | ESR1ESR2LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202686-A1 | HEAT-SENSITIVE RECORDING MATERIAL | OJI PAPER CO., LTD. (JP) | 2012-08-09 | — | — | US | disclosed |