Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112516 | 0.83 | NPC1 (0.61) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL975117 | 0.83 | ALDH1A1 (0.68) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL6644387 | 0.78 | SMN1; SMN2 (0.61) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL411359 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL27637513 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL1207703 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL8548846 | 0.76 | KMT2A (0.60) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL1648665 | 0.76 | TSHR (0.51) | ALDH1A1CTSDNPC1RAB9AGAA | |
| SCHEMBL10613860 | 0.75 | ALDH1A1 (0.68) | ALDH1A1CTSDGAAHTTNCOA1 | |
| SCHEMBL5705801 | 0.75 | TSHR (0.59) | ALDH1A1CTSDNPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2674420-B1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | IHARA CHEMICAL IND CO (JP) | 2016-01-27 | — | — | EP | claimed |
| CN-103415510-B | The preparation method of aminophenyl pyrimidyl alcohol derivate and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2016-01-13 | — | — | CN | claimed |
| EP-2674420-A1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2013-12-18 | — | — | EP | claimed |
| CN-103415510-A | Method for producing aminophenyl pyrimidinyl alcohol derivative, and synthesis intermediate thereof | IHARA CHEMICAL IND CO | 2013-11-27 | — | — | CN | claimed |
| EP-2674420-B1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | IHARA CHEMICAL IND CO (JP) | 2016-01-27 | — | — | EP | disclosed |
| CN-103415510-B | The preparation method of aminophenyl pyrimidyl alcohol derivate and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2016-01-13 | — | — | CN | disclosed |
| CN-103415510-B | The preparation method of aminophenyl pyrimidyl alcohol derivate and synthetic intermediate thereof | IHARA CHEMICAL INDUSTRY CO.,LTD. (JP) | 2016-01-13 | — | — | CN | disclosed |
| EP-2674420-A1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2013-12-18 | — | — | EP | disclosed |
| EP-2674420-A1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2013-12-18 | — | — | EP | disclosed |
| CN-103415510-A | Method for producing aminophenyl pyrimidinyl alcohol derivative, and synthesis intermediate thereof | IHARA CHEMICAL IND CO | 2013-11-27 | — | — | CN | disclosed |
| CN-103415510-A | Method for producing aminophenyl pyrimidinyl alcohol derivative, and synthesis intermediate thereof | IHARA CHEMICAL IND CO | 2013-11-27 | — | — | CN | disclosed |
| WO-2012105263-A1 | METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF | イハラケミカル工業株式会社 (JP) | 2012-08-09 | — | — | WO | disclosed |