Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.65 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345968 | 0.88 | HTT (0.60) | DDB1CRBNALDH1A1HTTNPC1 | |
| SCHEMBL15477732 | 0.87 | HTT (0.58) | DDB1CRBNALDH1A1HTTNPC1 | |
| SCHEMBL12270646 | 0.81 | KMT2A (0.60) | DDB1CRBNALDH1A1HTTNPC1 | |
| SCHEMBL19370841 | 0.79 | CRBN (1.00) | DDB1CRBNALDH1A1IKZF3 | |
| SCHEMBL5742534 | 0.79 | CRBN (1.00) | DDB1CRBNALDH1A1IKZF3 | |
| SCHEMBL20773238 | 0.79 | CRBN (1.00) | DDB1CRBNALDH1A1IKZF3 | |
| SCHEMBL2465110 | 0.78 | HTT (0.83) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL3459886 | 0.78 | HTT (0.83) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL29742388 | 0.78 | HTT (0.83) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL3460628 | 0.78 | HTT (0.83) | ALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | claimed |