Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 16/20 | 0.59 |
| ▸ | MAOB | P27338 | 14/20 | 0.59 |
| ▸ | MAOA | P21397 | 10/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903561 | 1.00 | KDM1A (0.59) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL1667828 | 0.90 | KCNH2 (0.56) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL1667830 | 0.90 | KCNH2 (0.56) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL13469006 | 0.90 | KCNH2 (0.56) | KDM1AMAOBMAOAKCNH2RAB9A | |
| Hydrochloric Acid SCHEMBL13277807 | 0.89 | KCNH2 (0.55) | KDM1AMAOBMAOAKCNH2RAB9A | |
| Hydrochloric Acid SCHEMBL13277806 | 0.89 | KCNH2 (0.55) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL1667796 | 0.89 | KDM1A (0.54) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL1667636 | 0.86 | KCNH2 (0.56) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL1667637 | 0.86 | KCNH2 (0.56) | KDM1AMAOBMAOAKCNH2RAB9A | |
| SCHEMBL2344692 | 0.83 | KDM1A (0.79) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486002-B1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | ORYZON GENOMICS SA (ES) | 2019-03-27 | — | — | EP | disclosed |
| EP-2486002-A1 | SUBSTITUTED HETEROARYL- AND ARYL- CYCLOPROPYLAMINE ACETAMIDES AND THEIR USE | Oryzon Genomics, S.A. (ES) | 2012-08-15 | — | — | EP | disclosed |