SCHEMBL2344692

SCHEMBL2344692

CN1CCN(C(=O)CN[C@@H]2C[C@H]2c2ccc(OCc3ccc(C#N)cc3)cc2)CC1

nearest known ligand 0.79

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 20/20 0.79
MAOB P27338 20/20 0.79
MAOA P21397 12/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2344695 1.00 KDM1A (0.79) KDM1AMAOBMAOA
SCHEMBL12283362 1.00 KDM1A (0.79) KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL2361693 0.99 KDM1A (0.78) KDM1AMAOBMAOA
Hydrochloric Acid SCHEMBL2361697 0.99 KDM1A (0.78) KDM1AMAOBMAOA
SCHEMBL2546102 0.89 KDM1A (1.00) KDM1AMAOBMAOA
SCHEMBL19092432 0.89 KDM1A (1.00) KDM1AMAOBMAOA
SCHEMBL12242308 0.89 KDM1A (1.00) KDM1AMAOBMAOA
SCHEMBL12242316 0.89 KDM1A (1.00) KDM1AMAOBMAOA
SCHEMBL2340542 0.89 KDM1A (1.00) KDM1AMAOBMAOA
SCHEMBL1287580 0.89 KDM1A (1.00) KDM1AMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9616058-B2 Potent selective LSD1 inhibitors and dual LSD1/MAO-B inhibitors for antiviral use ORYZON GENOMICS, S.A. (ES) 2017-04-11 US claimed
EP-2361242-B1 OXIDASE INHIBITORS AND THEIR USE ORYZON GENOMICS SA (ES) 2018-08-01 EP disclosed
US-8524717-B2 Oxidase inhibitors and their use ORYZON GENOMICS, S.A. (ES) 2013-09-03 US disclosed
US-20110263604-A1 Oxidase inhibitors and their use ORYZON GENOMICS, S.A. (ES) 2011-10-27 US disclosed
EP-2361242-A1 OXIDASE INHIBITORS AND THEIR USE Oryzon Genomics, S.A. (ES) 2011-08-31 EP disclosed
WO-2010043721-A1 OXIDASE INHIBITORS AND THEIR USE ORYZON GENOMICS, S.A. (ES) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263604-A1 Oxidase inhibitors and their use MAOA, PNPO, MAOB KDM1A 920/4885MAOB 3/4885MAOA 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.