Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | GPR88 | Q9GZN0 | 12/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871559 | 0.81 | FFAR1 (0.46) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL27887834 | 0.81 | FFAR1 (0.46) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL27871560 | 0.81 | FFAR1 (0.46) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL1553939 | 0.80 | KDM4E (0.45) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL2498164 | 0.79 | FFAR1 (0.48) | FFAR1GPR88KDM4EGLACHRM1 | |
| SCHEMBL2498163 | 0.79 | FFAR1 (0.48) | FFAR1GPR88KDM4EGLACHRM1 | |
| SCHEMBL27871564 | 0.77 | FFAR1 (0.41) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL11903485 | 0.75 | FFAR1 (0.58) | FFAR1GPR88ALDH1A1 | |
| SCHEMBL2501596 | 0.74 | KDM4E (0.53) | FFAR1GPR88KDM4EGLAALDH1A1 | |
| SCHEMBL2501600 | 0.74 | KDM4E (0.53) | FFAR1GPR88KDM4EGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486030-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |