Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | GPR88 | Q9GZN0 | 17/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388679 | 0.82 | PARP10 (0.58) | ALDH1A1TSHR | |
| SCHEMBL15121578 | 0.78 | FFAR1 (0.54) | FFAR1GPR88ALDH1A1TSHR | |
| SCHEMBL2498164 | 0.78 | FFAR1 (0.48) | FFAR1GPR88ALDH1A1 | |
| SCHEMBL2498163 | 0.78 | FFAR1 (0.48) | FFAR1GPR88ALDH1A1 | |
| SCHEMBL13560360 | 0.77 | FFAR1 (0.53) | FFAR1GPR88ALDH1A1TSHR | |
| SCHEMBL13560359 | 0.77 | FFAR1 (0.53) | FFAR1GPR88ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL2523106 | 0.77 | FFAR1 (0.52) | FFAR1GPR88ALDH1A1TSHR | |
| SCHEMBL10845631 | 0.77 | MMP9 (0.64) | TSHR | |
| SCHEMBL13706519 | 0.77 | FFAR1 (0.63) | FFAR1GPR88ALDH1A1TSHR | |
| SCHEMBL15121855 | 0.76 | FFAR1 (0.51) | FFAR1GPR88ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486030-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |