Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 19/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.53 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.53 |
| ▸ | PSMD11 | O00231 | 2/20 | 0.53 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.53 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.53 |
| ▸ | PSMD3 | O43242 | 2/20 | 0.53 |
| ▸ | PSMC3 | P17980 | 2/20 | 0.53 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.53 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.53 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.53 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.53 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.53 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.53 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.53 |
| ▸ | PSMC2 | P35998 | 2/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904133 | 0.97 | PSMB5 (0.55) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL11904237 | 0.86 | PSMB5 (0.60) | PSMB5PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3746818 | 0.81 | PSMB5 (0.57) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL2328432 | 0.81 | PSMB5 (0.59) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL3755101 | 0.79 | PSMB5 (0.59) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| Hydrochloric Acid SCHEMBL3741550 | 0.79 | PSMB5 (0.61) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL3748205 | 0.78 | PSMB5 (0.59) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL4343744 | 0.78 | PSMB5 (0.59) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| SCHEMBL3747846 | 0.78 | PSMB5 (0.64) | PSMB5PSMB1PSMB11PSMD11PSMD12 | |
| Hydrochloric Acid SCHEMBL3746894 | 0.77 | PSMB5 (0.61) | PSMB5PSMB1PSMB11PSMD11PSMD12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212334-B1 | PROTEASOME INHIBITORS | MILLENNIUM PHARM INC (US) | 2012-08-15 | — | — | EP | disclosed |