Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920853 | 0.88 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL3103128 | 0.87 | CRHR1 (0.60) | CRHR1 | |
| SCHEMBL3107787 | 0.81 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL1613290 | 0.79 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL3107036 | 0.78 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL11904388 | 0.76 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL11903721 | 0.75 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL3231469 | 0.75 | CRHR1 (0.63) | CRHR1 | |
| SCHEMBL12693248 | 0.75 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL1613443 | 0.75 | CRHR1 (0.71) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487178-A1 | PYRAZOLOTHIAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |