Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29212654 | 0.77 | TBXAS1 (0.44) | KDM4EALDH1A1TBXAS1 | |
| SCHEMBL10910625 | 0.74 | — | — | |
| SCHEMBL12376565 | 0.73 | TBXAS1 (0.44) | TBXAS1 | |
| SCHEMBL9031096 | 0.73 | TBXAS1 (0.47) | KDM4EALDH1A1TBXAS1 | |
| SCHEMBL29305017 | 0.73 | TBXAS1 (0.50) | TBXAS1 | |
| SCHEMBL7283421 | 0.72 | TBXAS1 (0.54) | KDM4EALDH1A1TBXAS1 | |
| SCHEMBL11904892 | 0.71 | CYP19A1 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL11904846 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1TBXAS1 | |
| SCHEMBL9029776 | 0.70 | TBXAS1 (0.45) | KDM4EALDH1A1TBXAS1 | |
| SCHEMBL28982375 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438295-B1 | AZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SERONO SA (CH) | 2012-08-15 | — | — | EP | claimed |