Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RUNX1 | Q01196 | 3/20 | 0.47 |
| ▸ | CBFB | Q13951 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903504 | 0.91 | PDE10A (0.62) | PDE10ATRPV1KMT2ASCN10AKDM4E | |
| SCHEMBL11904599 | 0.90 | PDE10A (0.47) | PDE10ATRPV1KMT2AMAPTPKM | |
| SCHEMBL10284557 | 0.85 | PDE10A (0.58) | PDE10ATRPV1SCN10ARUNX1CBFB | |
| SCHEMBL10436145 | 0.84 | CYP1A2 (0.62) | KMT2AMAPTPKM | |
| SCHEMBL11903503 | 0.80 | PDE10A (0.50) | PDE10ATRPV1KMT2ASCN10AKDM4E | |
| SCHEMBL9194512 | 0.80 | CYP1A2 (0.61) | PDE10AKMT2A | |
| SCHEMBL11903493 | 0.80 | RUNX1 (0.58) | PDE10ATRPV1SCN10ATDP1RUNX1 | |
| Hydrochloric Acid SCHEMBL11903522 | 0.79 | PDE10A (0.67) | PDE10ATRPV1KMT2AMAPTPKM | |
| SCHEMBL9721050 | 0.76 | KMT2A (0.82) | KMT2AMAPTPKMKDM4EMEN1 | |
| SCHEMBL11904659 | 0.76 | PDE10A (0.55) | PDE10ATRPV1SCN10AMAPTRUNX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293780-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | U.S. DEPARTMENT OF ENERGY (US) | 2012-10-23 | — | — | US | disclosed |
| US-8242284-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 2012-08-14 | — | — | US | disclosed |