Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RUNX1 | Q01196 | 7/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CBFB | Q13951 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.50 |
| ▸ | RHEB | Q15382 | 1/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903491 | 0.88 | RHEB (0.50) | RUNX1PDE10ATDP1CBFBTRPV1 | |
| SCHEMBL10284557 | 0.85 | PDE10A (0.58) | RUNX1PDE10ACBFBTRPV1SCN10A | |
| SCHEMBL11903504 | 0.83 | PDE10A (0.62) | RUNX1PDE10ACBFBTRPV1SCN10A | |
| SCHEMBL11904659 | 0.82 | PDE10A (0.55) | RUNX1PDE10ACBFBTRPV1SCN10A | |
| Hydrochloric Acid SCHEMBL11903456 | 0.81 | GRIN1 (0.65) | RUNX1PDE10ATDP1CBFBTRPV1 | |
| Hydrochloric Acid SCHEMBL11904760 | 0.81 | PDE10A (0.54) | RUNX1PDE10ACBFBTRPV1SCN10A | |
| Hydrochloric Acid SCHEMBL11903596 | 0.81 | GAA (0.61) | RUNX1PDE10ATDP1CBFBTRPV1 | |
| SCHEMBL12635909 | 0.80 | F10 (0.61) | TDP1NPSR1EGLN1F10 | |
| SCHEMBL31284816 | 0.80 | F10 (0.61) | TDP1NPSR1EGLN1F10 | |
| SCHEMBL5807305 | 0.80 | RUNX1 (0.56) | RUNX1PDE10ACBFBTRPV1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293780-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | U.S. DEPARTMENT OF ENERGY (US) | 2012-10-23 | — | — | US | disclosed |
| US-8242284-B1 | Anti-cancer agents based on 6-trifluoromethoxybenzimidazole derivatives and method of making | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 2012-08-14 | — | — | US | disclosed |