Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904473 | 0.90 | CHRM1 (0.63) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904633 | 0.89 | CHRM1 (0.54) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL4906414 | 0.88 | CHRM1 (0.73) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904684 | 0.87 | CHRM1 (0.48) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL4686256 | 0.87 | CHRM1 (0.72) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904620 | 0.86 | CHRM1 (0.77) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904820 | 0.86 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904522 | 0.86 | CHRM1 (0.59) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904793 | 0.84 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM3CHRM5 | |
| SCHEMBL11904800 | 0.83 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960389-B1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LTD (GB) | 2012-08-15 | — | — | EP | claimed |