Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753513 | 0.78 | JAK3 (0.36) | FDPS | |
| SCHEMBL8836046 | 0.68 | FDPS (0.38) | FDPS | |
| SCHEMBL27438643 | 0.68 | FDPS (0.35) | FDPS | |
| SCHEMBL27520126 | 0.68 | PI4KA (0.36) | FDPS | |
| SCHEMBL2451018 | 0.63 | FDPS (0.44) | FDPS | |
| SCHEMBL17965853 | 0.63 | FDPS (0.32) | FDPS | |
| SCHEMBL11611670 | 0.60 | FDPS (0.38) | FDPS | |
| SCHEMBL29141643 | 0.59 | HDAC1 (0.40) | FDPS | |
| SCHEMBL5033557 | 0.59 | FDPS (0.36) | FDPS | |
| SCHEMBL5062453 | 0.59 | FDPS (0.54) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486039-A1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | Sloan Kettering Institute For Cancer Research (US) | 2012-08-15 | — | — | EP | disclosed |