⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15855776 | 0.75 | NR1I2 (0.39) | — | |
| SCHEMBL1190098 | 0.74 | NR1I2 (0.36) | — | |
| SCHEMBL4838777 | 0.73 | HDAC4 (0.34) | — | |
| SCHEMBL4842515 | 0.73 | HDAC4 (0.34) | — | |
| SCHEMBL17312786 | 0.68 | RIPK1 (0.39) | — | |
| SCHEMBL2235808 | 0.68 | RIPK1 (0.39) | — | |
| SCHEMBL23309895 | 0.66 | POLB (0.36) | — | |
| SCHEMBL6158610 | 0.64 | — | — | |
| SCHEMBL3013805 | 0.64 | BRD4 (0.40) | — | |
| SCHEMBL2282815 | 0.63 | SCN9A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130045962-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2013-02-21 | — | — | US | disclosed |
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |
| EP-2217226-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090306066-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2009-12-10 | — | — | US | disclosed |
| WO-2009061879-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |