Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 17/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8908701 | 0.87 | ESR1 (0.44) | ESR1ESR2TP53 | |
| SCHEMBL5617933 | 0.84 | ESR1 (0.53) | ESR1ESR2AR | |
| SCHEMBL23140662 | 0.83 | ESR1 (0.51) | ESR1ESR2AR | |
| SCHEMBL30708954 | 0.78 | ESR1 (0.57) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL31666450 | 0.78 | ESR1 (0.57) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL311579 | 0.78 | ESR1 (0.57) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL5873699 | 0.78 | ESR1 (0.57) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL8459895 | 0.78 | ESR1 (0.39) | ESR1ESR2ARTDP1 | |
| SCHEMBL8735289 | 0.77 | ESR1 (0.61) | ESR1ESR2ARVDR | |
| SCHEMBL17803638 | 0.75 | ESR1 (0.42) | ESR1ESR2ARTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208936-A1 | POLYCARBONATE COMPOSITIONS WITH IMPROVED MELT STABILITY | BAYER MATERIALSCIENCE AG (DE) | 2012-08-16 | — | — | US | disclosed |