Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 18/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | GRK5 | P34947 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935943 | 0.93 | ESR1 (0.54) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL8735289 | 0.87 | ESR1 (0.61) | ESR1ESR2AR | |
| SCHEMBL14760247 | 0.86 | ALOX15 (0.54) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL7972245 | 0.86 | ESR1 (0.54) | ESR1ESR2ARTDP1 | |
| SCHEMBL7969173 | 0.85 | ESR1 (0.61) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL9717792 | 0.84 | RORC (0.46) | ESR1ESR2ARCHEK1FYN | |
| SCHEMBL2028819 | 0.83 | ESR1 (0.72) | ESR1ESR2AR | |
| SCHEMBL30721115 | 0.83 | ESR1 (0.72) | ESR1ESR2AR | |
| SCHEMBL30726442 | 0.83 | ESR1 (0.72) | ESR1ESR2AR | |
| SCHEMBL7101111 | 0.83 | ESR1 (0.53) | ESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091302-B2 | Process for the preparation of polycarbonate | BAYER MATERIALSCIENCE AG (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20050239995-A1 | Process for the preparation of polycarbonate | BAYER MATERIALSCIENCE AG | 2005-10-27 | — | — | US | disclosed |