Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191156 | 1.00 | CA1 (0.48) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL28045116 | 0.85 | CA1 (0.62) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL590923 | 0.85 | CA1 (0.62) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL4710881 | 0.82 | PARP1 (0.48) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL875040 | 0.80 | CA1 (0.46) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL20873266 | 0.80 | CA1 (0.46) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL31541868 | 0.79 | SLC6A2 (0.43) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL10748694 | 0.79 | CA1 (0.40) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL4961994 | 0.78 | SLC18A2 (0.55) | KMT2A | |
| SCHEMBL15062243 | 0.78 | SLC18A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893056-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-02-22 | — | — | US | disclosed |