Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15668140 | 0.87 | SMN1; SMN2 (0.46) | KMT2A | |
| SCHEMBL13738630 | 0.85 | DPP4 (0.47) | KMT2A | |
| SCHEMBL15667954 | 0.85 | DPP4 (0.47) | KMT2A | |
| SCHEMBL15608026 | 0.85 | DPP4 (0.47) | KMT2A | |
| SCHEMBL23459127 | 0.84 | SCD5 (0.57) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL908981 | 0.84 | SCD5 (0.57) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6970610 | 0.84 | MEN1 (0.54) | SLC18A2KCNH2HRH3MEN1NPC1 | |
| SCHEMBL23236372 | 0.82 | SPHK1 (0.55) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL23236376 | 0.82 | SPHK1 (0.55) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL15668142 | 0.81 | DPP4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |