SCHEMBL11908054

SCHEMBL11908054

CCC(C(=O)O)C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.36
LMNA P02545 1/20 0.36
EPHX2 P34913 3/20 0.34
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8193850 0.87 KDM4E (0.35) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL724697 0.84 KDM4E (0.37) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL3293689 0.77 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL2858536 0.76 ACE2 (0.42) EPHX2
SCHEMBL6839063 0.76 KDM4E (0.33) KDM4ELMNAEPHX2ALDH1A1
SCHEMBL13370548 0.74 KDM4E (0.36) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL5053687 0.74 KDM4E (0.37) KDM4ELMNAEPHX2
SCHEMBL22941781 0.73 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL14053439 0.73 GRM5 (0.47) KDM4ELMNA
SCHEMBL25946742 0.73 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450440-B2 Method for purifying polymer and polymer MITSUI CHEMICALS, INC. (JP) 2013-05-28 US disclosed
US-20120208976-A1 METHOD FOR PURIFYING POLYMER AND POLYMER MITSUI CHEMICALS, INC (JP) 2012-08-16 US disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed