SCHEMBL724697

SCHEMBL724697

O=C(O)C(CO)C1CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
LMNA P02545 1/20 0.37
EPHX2 P34913 4/20 0.35
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11908054 0.84 KDM4E (0.36) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL8193850 0.81 KDM4E (0.35) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL14053439 0.74 GRM5 (0.47) KDM4ELMNA
SCHEMBL22941781 0.74 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL25946742 0.74 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL3293689 0.74 KDM4E (0.39) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL4666821 0.73 KDM4E (0.33) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL2070938 0.71 KDM4E (0.41) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL4743391 0.71 KDM4E (0.37) KDM4ELMNAEPHX2ALDH1A1TDP1
SCHEMBL5053687 0.71 KDM4E (0.37) KDM4ELMNAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043608-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2024-02-08 US claimed
US-10633484-B2 Method and composition for improving adhesion of metathesis compositions to substrates MATERIA, INC. (US) 2020-04-28 US claimed
US-6316565-B1 FOR FORMING PATTERNS OF INTEGRATED SEMICONDUCTOR DEVICE, RESOLUTION IN PHOTOLITHOGRAPHY HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-11-13 US claimed
US-12043573-B2 Adhesion promoters and gel-modifiers for olefin metathesis compositions MATERIA, INC. (US) 2024-07-23 US disclosed
US-12036078-B2 Oral products and methods for producing the same PolySpectra, Inc. (US) 2024-07-16 US disclosed
WO-2024118568-A1 METHODS OF MAKING COMPOSITIONS FROM OLEFIN METATHESIS PHOTOPOLYMERS PolySpectra, Inc. (US) 2024-06-06 WO disclosed
US-20240043608-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2024-02-08 US disclosed
US-20230391945-A1 OLEFIN METATHESIS PHOTOPOLYMERS NATIONAL SCIENCE FOUNDATION 2023-12-07 US disclosed
CN-108779134-B Metal carbene olefin metathesis catalysts 优美科股份公司及两合公司 2023-10-03 CN disclosed
US-11725077-B2 Olefin metathesis photopolymers PolySpectra, Inc. (US) 2023-08-15 US disclosed
WO-2023023188-A1 METHODS OF MAKING COMPOSITIONS FROM OLEFIN METATHESIS PHOTOPOLYMERS PolySpectra, Inc. (US) 2023-02-23 WO disclosed
US-8324334-B2 Telechelic olefin metathesis polymers from renewable feedstocks MATERIA, INC. (US) 2012-12-04 US disclosed
WO-2012026980-A2 VARTM FLOW MODIFICATIONS FOR LOW VISCOSITY RESIN SYSTEMS MATERIA, INC. (US) 2012-03-01 WO disclosed
US-8067623-B2 Producing waxes from soybean oil; ruthenium alkylidene catalytic, simultaneous opening and inserting ELEVANCE RENEWABLE SCIENCES, INC. (US) 2011-11-29 US disclosed
EP-2321363-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS Materia, Inc. (US) 2011-05-18 EP disclosed
WO-2010021740-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA, INC. (US) 2010-02-25 WO disclosed
EP-2046719-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE Elevance Renewable Sciences, Inc. (US) 2009-04-15 EP disclosed
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like WILMAR TRADING PTE LTD (SG) 2008-03-13 US disclosed
WO-2008008440-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE ELEVANCE RENEWABLE SCIENCES, INC. (US) 2008-01-17 WO disclosed
US-6316565-B1 FOR FORMING PATTERNS OF INTEGRATED SEMICONDUCTOR DEVICE, RESOLUTION IN PHOTOLITHOGRAPHY HYUNDAI ELECTRONICS INDUSTRIES CO., LTD. (KR) 2001-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like SQLE, COASY, ALOX12 KDM4E 4258/4885LMNA 4682/4885EPHX2 166/4885
US-12036078-B2 Oral products and methods for producing the same CROCC, RPAP1, RUVBL1 KDM4E 706/4885LMNA 634/4885EPHX2 603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.