Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.46 |
| ▸ | FASN | P49327 | 5/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22220762 | 1.00 | BRD4 (0.46) | BRD4FASNP2RX3PIK3CDALDH1A2 | |
| SCHEMBL14400 | 1.00 | BRD4 (0.46) | BRD4FASNP2RX3PIK3CDALDH1A2 | |
| SCHEMBL22220897 | 0.94 | BRD4 (0.46) | BRD4FASNPIK3CDALDH1A2ALDH1A1 | |
| SCHEMBL10585 | 0.94 | BRD4 (0.46) | BRD4FASNPIK3CDALDH1A2ALDH1A1 | |
| SCHEMBL10584 | 0.94 | BRD4 (0.46) | BRD4FASNPIK3CDALDH1A2ALDH1A1 | |
| SCHEMBL10940 | 0.93 | BRD4 (0.49) | BRD4FASNP2RX3PIK3CDALDH1A2 | |
| SCHEMBL22220920 | 0.93 | BRD4 (0.49) | BRD4FASNP2RX3PIK3CDALDH1A2 | |
| SCHEMBL10939 | 0.93 | BRD4 (0.49) | BRD4FASNP2RX3PIK3CDALDH1A2 | |
| SCHEMBL22220803 | 0.91 | FASN (0.53) | BRD4FASNP2RX3PIK3CD | |
| SCHEMBL10015 | 0.91 | FASN (0.53) | BRD4FASNP2RX3PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | BRD4 277/4885FASN 1/4885P2RX3 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.