Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 11/20 | 0.67 |
| ▸ | BRD4 | O60885 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | MELK | Q14680 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363 | 1.00 | FASN (0.67) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL22220828 | 1.00 | FASN (0.67) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL11047 | 0.94 | FASN (0.59) | FASNBRD4P2RX3 | |
| SCHEMBL22220918 | 0.94 | FASN (0.59) | FASNBRD4P2RX3 | |
| SCHEMBL11046 | 0.94 | FASN (0.59) | FASNBRD4P2RX3 | |
| SCHEMBL22220919 | 0.93 | FASN (0.67) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL10561 | 0.93 | FASN (0.67) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL10562 | 0.93 | FASN (0.67) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL10852 | 0.91 | FASN (0.64) | FASNBRD4ACACBACACAMELK | |
| SCHEMBL10853 | 0.91 | FASN (0.64) | FASNBRD4ACACBACACAMELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | FASN 1/4885BRD4 277/4885ACACB 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.