Dyrene

Dyrene

SCHEMBL1191351

C=CC(=O)O.Clc1nc(Cl)nc(Nc2ccccc2Cl)n1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.71
▸ NFKB1 P19838 1/20 0.47
▸ ULK1 O75385 1/20 0.46
▸ RAD52 P43351 1/20 0.46
▸ HDAC3 O15379 1/20 0.46
▸ HDAC1 Q13547 1/20 0.46
▸ HDAC2 Q92769 1/20 0.46
▸ HDAC6 Q9UBN7 1/20 0.46
▸ MAPT P10636 4/20 0.44
▸ KMT2A Q03164 3/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ IGF1R P08069 1/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CXCL8 P10145 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.42
▸ AURKA O14965 4/20 0.42
▸ JAK2 O60674 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dyrene SCHEMBL10917575 0.90 TSHR (0.73) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL2342691 0.86 TSHR (0.77) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL6579552 0.86 TSHR (0.77) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL1254529 0.86 TSHR (0.89) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL11351922 0.86 TSHR (0.89) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL11744896 0.85 TSHR (0.75) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL10874656 0.84 TSHR (0.80) TSHRNFKB1ULK1RAD52HDAC3
Dyrene SCHEMBL9484476 0.84 TSHR (0.92) TSHRNFKB1RAD52HDAC3HDAC1
Dyrene SCHEMBL13280 0.84 TSHR (1.00) TSHRNFKB1RAD52HDAC3HDAC1
Dyrene SCHEMBL8166670 0.84 TSHR (1.00) TSHRNFKB1RAD52HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431738-A Triazine acrylic acid epoxy resin, preparation method and application thereof 广东三求光固材料股份有限公司 2025-02-14 — — CN claimed
US-8894263-B2 Optical plate, display apparatus having the same, and method of manufacturing the optical plate SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-25 — — US claimed
CN-103305135-A Photocuring vanishing glue used for adhering capacitive touch screens and preparation method thereof SHENZHEN FISHER IND CO LTD 2013-09-18 — — CN claimed
US-20120257412-A1 OPTICAL PLATE, DISPLAY APPARATUS HAVING THE SAME, AND METHOD OF MANUFACTURING THE OPTICAL PLATE SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-11 — — US claimed
CN-119431738-A Triazine acrylic acid epoxy resin, preparation method and application thereof 广东三求光固材料股份有限公司 2025-02-14 — — CN disclosed
US-20240083152-A1 TRANSFER SHEET, DECORATIVE MOLDED PRODUCT, AND METHOD FOR MANUFACTURING DECORATIVE MOLDED PRODUCT Nissha Co., Ltd. (JP) 2024-03-14 — — US disclosed
CN-117597201-A Method for producing film and film 柯尼卡美能达株式会社 2024-02-23 — — CN disclosed
CN-117083169-A Transfer sheet, decorative molded article, and method for producing decorative molded article NISSHA株式会社 2023-11-17 — — CN disclosed
EP-2506090-B1 Computer-generated hologram, reflector using a computer-generated hologram, and reflective liquid crystal display DAINIPPON PRINTING CO LTD (JP) 2016-12-07 — — EP disclosed
US-8894263-B2 Optical plate, display apparatus having the same, and method of manufacturing the optical plate SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-25 — — US disclosed
EP-1752307-B1 COLORING MATERIAL RECEPTOR SHEET WITH RELIEF LAYER, AND IMAGE FORMING METHOD USING IT DAINIPPON PRINTING CO LTD (JP) 2014-04-30 — — EP disclosed
CN-103305135-A Photocuring vanishing glue used for adhering capacitive touch screens and preparation method thereof SHENZHEN FISHER IND CO LTD 2013-09-18 — — CN disclosed
US-5530609-A Magnetic recording/reproducing method using a thin film magnetic TDK CORPORATION (JP) 1996-06-25 — — US disclosed
EP-0627729-A2 Magnetic recording/reproducing method TDK Corporation (JP) 1994-12-07 — — EP disclosed
EP-0201323-B1 Article incorporating a transparent hologramm DAINIPPON PRINTING CO LTD (JP) 1994-08-17 — — EP disclosed
EP-0609683-A1 Relief hologram and process for producing a relief hologram DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1994-08-10 — — EP disclosed
US-5182693-A Magnetic disk TDK CORPORATION (JP) 1993-01-26 — — US disclosed
US-5160761-A Coating, leveling in solvent vapor TDK CORPORATION (JP) 1992-11-03 — — US disclosed
US-4856857-A Hologram DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1989-08-15 — — US disclosed
EP-0201323-A2 Article incorporating a transparent hologramm DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1986-11-12 — — EP disclosed
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