Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6372017 | 0.91 | MAPT (0.43) | KMT2ATSHRMAPTMAPK1KDM4E | |
| SCHEMBL2673669 | 0.90 | KMT2A (0.51) | KMT2AMAPTKDM4EPOLBHTT | |
| SCHEMBL6372581 | 0.90 | ALDH1A1 (0.42) | KMT2ATSHRMAPTMAPK1HSD17B10 | |
| Hydrochloric Acid SCHEMBL2673197 | 0.90 | KDM4E (0.42) | KMT2ATSHRMAPTMAPK1KDM4E | |
| SCHEMBL6371055 | 0.90 | KDM4E (0.42) | KMT2ATSHRMAPTMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL2674685 | 0.89 | ALDH1A1 (0.42) | KMT2ATSHRMAPTMAPK1HSD17B10 | |
| SCHEMBL6371076 | 0.89 | KDM4E (0.42) | KMT2ATSHRMAPTMAPK1KDM4E | |
| SCHEMBL6371794 | 0.88 | ALDH1A1 (0.40) | KMT2AMAPTKDM4EPOLB | |
| SCHEMBL6371080 | 0.88 | MAPT (0.39) | KMT2AMAPTMAPK1KDM4EPOLB | |
| SCHEMBL6371039 | 0.88 | MAPK1 (0.53) | KMT2ATSHRMAPTMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202795-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | PARP1, PARP2, PARP3 | KMT2A 1291/4885TSHR 2825/4885MAPT 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.