⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL666843 | 0.82 | — | — | |
| SCHEMBL110314 | 0.82 | — | — | |
| SCHEMBL4086483 | 0.82 | — | — | |
| SCHEMBL19457696 | 0.82 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL5497328 | 0.80 | — | — | |
| Succinimide SCHEMBL3193335 | 0.74 | CRBN (0.50) | — | |
| Formamide SCHEMBL9742185 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL9096697 | 0.70 | CYP1A2 (0.41) | — | |
| SCHEMBL1115431 | 0.68 | — | — | |
| SCHEMBL13494457 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242105-B2 | Structural mimetics of proline-rich peptides and the pharmaceutical use thereof | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2012-08-14 | — | — | US | disclosed |
| US-20110034438-A1 | STRUCTURAL MIMETICS OF PROLINE-RICH PEPTIDES AND THE PHARMACEUTICAL USE THEREOF | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2011-02-10 | — | — | US | disclosed |