Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400653 | 0.91 | GPR119 (0.48) | GPR119SMOMEN1KMT2A | |
| SCHEMBL2394313 | 0.87 | GPR119 (0.51) | GPR119SMODEGS1DGAT1CHRM4 | |
| SCHEMBL13534676 | 0.83 | GPR119 (0.44) | GPR119SMODEGS1DGAT1PPARG | |
| SCHEMBL13534631 | 0.77 | GPR119 (0.62) | GPR119SMO | |
| SCHEMBL1296307 | 0.76 | GPR119 (0.48) | GPR119DEGS1DGAT1PPARGPPARD | |
| SCHEMBL4397904 | 0.76 | DEGS1 (0.39) | GPR119SMOENPP2DEGS1DGAT1 | |
| SCHEMBL2393744 | 0.75 | GPR119 (0.47) | GPR119TMEM97SIGMAR1ENPP2DEGS1 | |
| SCHEMBL2394461 | 0.75 | GPR119 (0.47) | GPR119TMEM97SIGMAR1ENPP2DEGS1 | |
| SCHEMBL1296337 | 0.75 | GPR119 (0.46) | GPR119ENPP2DEGS1DGAT1PPARG | |
| SCHEMBL13535138 | 0.75 | GPR119 (0.45) | GPR119ENPP2DEGS1DGAT1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321308-B9 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2012-08-08 | — | — | EP | disclosed |