SCHEMBL11920587

SCHEMBL11920587

CCc1nn2c(-c3c(O)cc(COC)cc3OC)c(C)oc2c1N(CC(C)C)CC1CCOCC1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 20/20 0.54
ERG P11308 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1661751 0.95 CRHR1 (0.58) CRHR1ERG
SCHEMBL11920892 0.92 CRHR1 (0.56) CRHR1
SCHEMBL1662891 0.88 CRHR1 (0.66) CRHR1ERG
SCHEMBL1662895 0.86 CRHR1 (0.62) CRHR1
SCHEMBL12792173 0.86 CRHR1 (0.52) CRHR1ERG
SCHEMBL11920588 0.85 CRHR1 (0.65) CRHR1ERG
SCHEMBL1660713 0.84 CRHR1 (0.63) CRHR1ERG
SCHEMBL1661744 0.84 CRHR1 (0.59) CRHR1ERG
SCHEMBL11920839 0.83 CRHR1 (0.51) CRHR1ERG
SCHEMBL1660798 0.82 CRHR1 (0.57) CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2487177-A1 PYRAZOLOXAZOLE COMPOUND Eisai R&D Management Co., Ltd. (JP) 2012-08-15 EP disclosed