SCHEMBL11921030

SCHEMBL11921030

Cc1ccc2c(oc3ccccc32)c1N1C=CN(c2ccccc2)C1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
PPARG P37231 4/20 0.35
RXFP1 Q9HBX9 4/20 0.35
NR2E3 Q9Y5X4 4/20 0.35
NCOR2 Q9Y618 4/20 0.35
NPSR1 Q6W5P4 3/20 0.35
LMNA P02545 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
CYP2C19 P33261 1/20 0.34
PGR P06401 1/20 0.34
HSD17B10 Q99714 3/20 0.33
HTT P42858 3/20 0.33
MAPT P10636 2/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
KDM4E B2RXH2 2/20 0.33
HCRTR1 O43613 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349245 1.00 ALDH1A1 (0.35) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL19999701 1.00 ALDH1A1 (0.35) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL19999699 0.90 MEN1 (0.38) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL21074287 0.90 MEN1 (0.38) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL21074272 0.89 ALDH1A1 (0.33) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL19999705 0.89 ALDH1A1 (0.33) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL24425940 0.87 MAOB (0.34)
SCHEMBL11921026 0.86 MEN1 (0.34) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL13843648 0.86 MEN1 (0.34) ALDH1A1PPARGRXFP1NR2E3NCOR2
SCHEMBL23613653 0.86 MEN1 (0.34) ALDH1A1PPARGRXFP1NR2E3NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LIMITED (IE) 2022-05-12 US disclosed
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics UDC IRELAND LIMITED (IE) 2021-11-30 US disclosed
EP-3492480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-20 EP disclosed
US-20200373503-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2020-11-26 US disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed
EP-2493906-B1 HETEROLEPTIC CARBEN COMPLEXES AND THEIR USE IN ORGANIG ELECTRONICS BASF SE (DE) 2015-10-21 EP disclosed
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-08-16 US disclosed
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-08-16 US disclosed
WO-2011051404-A1 HETEROLEPTIC CARBENE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2011-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885PPARG 985/4885RXFP1 4773/4885
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB ALDH1A1 3145/4885PPARG 692/4885RXFP1 4734/4885
US-20200373503-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885PPARG 985/4885RXFP1 4773/4885
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics OCIAD2, OCIAD1, CLTB ALDH1A1 3051/4885PPARG 985/4885RXFP1 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.