SCHEMBL11921934

SCHEMBL11921934

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@H]2C[C@H](O)[C@H](O[C@H]3OC(CO)[C@H](O[C@H]4C[C@H](O)[C@H](O[C@H]5OC(CO)[C@@H](O[C@H]6C[C@H](O)[C@H](O[C@@H]7OC(COS(=O)(=O)O)[C@H](O[C@H]8C[C@H](O)[C@H](O)CO8)[C@H](O)C7N)CO6)[C@H](O)C5N)CO4)[C@H](O)C3N)CO2)[C@H](O)C1N

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BLM P54132 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ FGF1 P05230 3/20 0.37
▸ MEN1 O00255 1/20 0.34
▸ LRAT O95237 1/20 0.34
▸ TRPV1 Q8NER1 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16656556 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11921942 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997482 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11921923 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997485 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997483 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997478 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997469 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11921938 1.00 BLM (0.38) BLMRECQLTDP1FGF1MEN1
SCHEMBL11997463 0.96 FGF1 (0.35) BLMRECQLTDP1FGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9527930-B2 FGF receptor-activating N-sulfate oligosaccharides, preparation thereof, and therapeutic use thereof SANOFI (FR) 2016-12-27 — — US disclosed
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120202769-A1 FGF RECEPTOR-ACTIVATING N-SULFATE OLIGOSACCHARIDES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF FGFR1, FGF1, FGF2 BLM 4746/4885RECQL 3828/4885TDP1 4871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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