FGF1

Fibroblast growth factor 1 · P05230 · FGF1 on Sugi Atlas →

9,460 patent compounds predicted against FGF1, 4,052 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL3804442 SCHEMBL3804442 0.62 11/20
SCHEMBL2058821 SCHEMBL2058821 0.59 9/20
SCHEMBL2059338 SCHEMBL2059338 0.54 9/20
Sucrosofate Sucrosofate (SCHEMBL3086839) 0.48 9/20
Potassium Ion Potassium Ion (SCHEMBL380009) 0.32 9/20
Water Water (SCHEMBL6357796) 0.32 9/20
SCHEMBL4899810 SCHEMBL4899810 0.64 8/20
SCHEMBL3700622 SCHEMBL3700622 0.59 8/20
SCHEMBL4895055 SCHEMBL4895055 0.59 8/20
SCHEMBL4902478 SCHEMBL4902478 0.59 8/20
SCHEMBL2507113 SCHEMBL2507113 0.53 8/20
SCHEMBL1787297 SCHEMBL1787297 0.50 8/20
SCHEMBL4904646 SCHEMBL4904646 0.70 7/20
SCHEMBL4906384 SCHEMBL4906384 0.70 7/20
SCHEMBL4180806 SCHEMBL4180806 0.69 7/20
SCHEMBL3691749 SCHEMBL3691749 0.68 7/20
SCHEMBL728827 SCHEMBL728827 0.61 7/20
SCHEMBL3391119 SCHEMBL3391119 0.61 7/20
SCHEMBL2059166 SCHEMBL2059166 0.57 7/20
SCHEMBL3135361 SCHEMBL3135361 0.57 7/20

Clinical trials — most relevant to FGF1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Etelcalcetide on Cardiac Hypertrophy in Hemodialysis Patients PHASE4COMPLETED
Role of Coenzyme Q10 in Chronic Kidney Disease PHASE4RECRUITING
Role of Vitamin K2 in Chronic Kidney Disease PHASE4RECRUITING
Nintedanib in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome Grade 0p-1-2 PHASE3COMPLETED
Fibroblast Growth Factor-1 (FGF-1) for the Treatment of Coronary Heart Disease PHASE2UNKNOWN
FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease PHASE1/PHASE2UNKNOWN
Dovitinib Lactate in Treating Patients With Pancreatic Neuroendocrine Tumors PHASE2WITHDRAWN
The Effectiveness of Allogenic Mesenchymal Stem Cells Therapy on Hair Regrowth in Androgenetic Alopecia. PHASE1/PHASE2ENROLLING_BY_INVITATION
Vitamin D Deficiency Treatment Outcomes After Non-ST-Segment Elevation Myocardial Infarction PHASE2UNKNOWN
Dovitinib(TKI258) in Patients With Castration-resistant Prostate Cancer PHASE2COMPLETED
An Open-label Phase II Study With SUTENT in Patients Suffering From Hormone Refractory Prostate Cancer PHASE2COMPLETED
In-office Repair of Chronic Tympanic Membrane Perforations PHASE1/PHASE2ACTIVE_NOT_RECRUITING
FGF-1 for Topical Administration for the Treatment of Diabetic or Venous Stasis Ulcers PHASE1COMPLETED
Safety Study of Topical Human FGF-1 for Wound Healing PHASE1UNKNOWN
Gene Expression and Tolerability Study of NV1FGF in Patients With Peripheral Artery Occlusive Disease Planned to Undergo Major Amputation PHASE1COMPLETED
Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2) In Gingival Recession Defects EARLY_PHASE1COMPLETED
Role of FGF21 in Breast Cancer nanNOT_YET_RECRUITING
Vitamin D Deficiency, Insulin Resistance and FGF-23 nanCOMPLETED
Fibroblast Growth Factor-23 (FGF-23) is Independently Associated With Left Ventricular Mass Index (LVMI) and Myocardial Performance Index (MPI) in Haemodialysis Patients nanUNKNOWN
Atrial Fibrillation in Relationship to Plasma Biomarkers nanUNKNOWN
Effect of Aloe Vera Gel and Manuka Honey on Radiation Induced Oral Mucositis nanUNKNOWN
Effectiveness of a rhGM-CSF-containing Gel on Promoting Recovery After 1927-nm Fractional Thulium Fiber Laser Treatment of Atrophic Acne Scars. nanCOMPLETED
Evaluate the Effect of Growth Hormone (GH) Treatment on Fibroblast Growth Factor 23, a Known Phosphaturic Agent nanCOMPLETED
Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia: A Systematic Review and Meta-analysis nanUNKNOWN
Baker Cyst Aspiration Combined With Platelet-rich Plasma Injection in Knee Osteoarthritis nanCOMPLETED
Investigation of Substrates Associated With the Recurrence of Atrial Fibrillation After PV Cryoablation nanCOMPLETED
Physiologic Regulation of FGF-23 nanCOMPLETED
Bone Markers and Bone Density Changes in Hyperperparathyroid Dialysis Patients Under Cinacalcet Treatment nanCOMPLETED
Platelet-Rich Plasma for Partial Rotator Cuff Tears nanNOT_YET_RECRUITING
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FGF1 binder may also engage these)

ProteinNameSimilarity
Q5NVQ3 1.000 Q5NVQ3 →
P20002 1.000 P20002 →
P34004 1.000 P34004 →
P61149 1.000 P61149 →
P19596 1.000 P19596 →
P03968 1.000 P03968 →
P61148 1.000 P61148 →
Q7SIF8 1.000 Q7SIF8 →
Q7M303 1.000 Q7M303 →
Q6PBT8 0.999 Q6PBT8 →
Q6I6M7 0.999 Q6I6M7 →
Q6GLR6 0.997 Q6GLR6 →
P48798 0.995 P48798 →
P15655 0.993 P15655 →
P12226 0.992 P12226 →
P13109 0.992 P13109 →
P03969 0.992 P03969 →
P20003 0.991 P20003 →
O89101 0.991 O89101 →
P48808 0.991 P48808 →
O88182 0.991 O88182 →
P48800 0.990 P48800 →
Q5RAY8 0.990 Q5RAY8 →
Q9N198 0.989 Q9N198 →
Q0VCA0 0.989 Q0VCA0 →
P21781 0.989 P21781 →
P79150 0.989 P79150 →
P48799 0.988 P48799 →
Q5D0X0 0.988 Q5D0X0 →
P36363 0.988 P36363 →