SCHEMBL11921992

SCHEMBL11921992

c1ccc2c(c1)c1ccccc1n2-c1ccc2c3ccccc3n(-c3ccc(-n4c5ccccc5c5ccc(-n6c7ccccc7c7ccccc76)cc54)cc3)c2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.67
KDM4E B2RXH2 1/20 0.67
ATM Q13315 1/20 0.67
GPR3 P46089 1/20 0.41
PTPN1 P18031 2/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
POLB P06746 1/20 0.39
HDAC4 P56524 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
PRSS1 P07477 1/20 0.39
ALDH1A1 P00352 2/20 0.37
MAT2A P31153 1/20 0.36
MAPK8 P45983 2/20 0.36
KMT2A Q03164 2/20 0.36
IL1R1 P14778 1/20 0.36
MAPK1 P28482 1/20 0.35
KIF11 P52732 1/20 0.35
PGR P06401 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921965 1.00 L3MBTL1 (0.67) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL30709570 0.96 L3MBTL1 (0.75) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL17038444 0.96 L3MBTL1 (0.75) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL13932471 0.96 L3MBTL1 (0.75) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL16409612 0.96 L3MBTL1 (0.75) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL11921973 0.94 L3MBTL1 (0.59) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL20232364 0.94 L3MBTL1 (0.72) L3MBTL1KDM4EATMPTPN1POLB
SCHEMBL11922005 0.94 L3MBTL1 (0.59) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL17676366 0.94 KDM4E (0.59) L3MBTL1KDM4EATMGPR3PTPN1
SCHEMBL17038435 0.94 L3MBTL1 (0.59) L3MBTL1KDM4EATMGPR3PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20170170404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-20170170404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF AR, DRD3, AHR L3MBTL1 717/4885KDM4E 2681/4885ATM 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.