SCHEMBL11921996

SCHEMBL11921996

c1ccc(-c2ccc(N(c3ccccc3)c3ccc4c5ccccc5n(-c5ccc(-n6c7ccccc7c7ccc(N(c8ccccc8)c8ccc(-c9ccccc9)cc8)cc76)cc5)c4c3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ATM Q13315 1/20 0.49
HDAC4 P56524 1/20 0.40
KMT2A Q03164 2/20 0.35
IL1R1 P14778 1/20 0.35
TSPO P30536 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
PTPN1 P18031 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11921957 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11922047 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11921976 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11922035 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11922069 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11921962 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11921980 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11922014 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11921977 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A
SCHEMBL11922033 1.00 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20170170404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-20170170404-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-15 US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF AR, DRD3, AHR L3MBTL1 717/4885KDM4E 2681/4885ATM 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.