SCHEMBL11922022

SCHEMBL11922022

c1ccc(-c2ccc(-n3c4ccccc4c4ccc(N(c5ccccc5)c5cccc(-c6cccc(N(c7ccccc7)c7ccc8c9ccccc9n(-c9ccc(-c%10ccccc%10)cc9)c8c7)c6)c5)cc43)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ KDM4E B2RXH2 2/20 0.45
▸ ATM Q13315 1/20 0.45
▸ HDAC4 P56524 1/20 0.38
▸ TSPO P30536 1/20 0.36
▸ KMT2A Q03164 2/20 0.33
▸ JAK2 O60674 1/20 0.33
▸ IL1R1 P14778 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ FEN1 P39748 1/20 0.33
▸ APP P05067 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ TNKS2 Q9H2K2 1/20 0.32
▸ PTPN1 P18031 2/20 0.32
▸ AKR1C4 P17516 1/20 0.31
▸ AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11922026 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL18960890 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL11922032 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL11921986 1.00 L3MBTL1 (0.45) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL24883233 0.99 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL11922023 0.99 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL24948930 0.99 L3MBTL1 (0.47) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL24949966 0.99 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL18310272 0.97 KDM4E (0.46) L3MBTL1KDM4EATMHDAC4TSPO
SCHEMBL24948719 0.97 L3MBTL1 (0.49) L3MBTL1KDM4EATMHDAC4TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 — — US disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 — — US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 — — US disclosed
US-20170117486-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 — — US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 — — US disclosed
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2012-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120203010-A1 CARBAZOLE COMPOUND AND USE THEREOF AR, DRD3, AHR L3MBTL1 717/4885KDM4E 2681/4885ATM 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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