SCHEMBL11922532

SCHEMBL11922532

CCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CCN(CCC)CCC)C5=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ TERT O14746 6/20 0.59
▸ FGFR1 P11362 2/20 0.47
▸ KDR P35968 2/20 0.47
▸ PDGFRA P16234 1/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ RGS12 O14924 2/20 0.47
▸ HTT P42858 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ PABPC1 P11940 1/20 0.47
▸ RECQL P46063 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ BCHE P06276 2/20 0.46
▸ ACHE P22303 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105127 0.92 TERT (0.69) STAT3HIF1ATERTMEN1RGS12
SCHEMBL7485132 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL418871 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL6263953 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18379137 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL284967 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL1105114 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL18376159 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL8071104 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR
SCHEMBL31071033 0.89 STAT3 (0.65) STAT3HIF1ATERTFGFR1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8237895-B2 Liquid crystal display device and method of manufacturing the same HITACHI DISPLAYS, LTD. (JP) 2012-08-07 — — US disclosed
US-20090153781-A1 Liquid Crystal Display Device and Method of Manufacturing the Same IPS ALPHA SUPPORT CO., LTD. (JP) 2009-06-18 — — US disclosed
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