Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958738 | 0.85 | ACHE (0.44) | ACHEEPHX1 | |
| SCHEMBL5535521 | 0.84 | ACHE (0.53) | ACHEEPHX1ALOX15 | |
| SCHEMBL18816748 | 0.82 | ACHE (0.36) | ACHE | |
| SCHEMBL3885584 | 0.81 | ACHE (0.38) | ACHE | |
| SCHEMBL18452390 | 0.81 | EPHX2 (0.49) | ACHE | |
| SCHEMBL18792724 | 0.81 | ACHE (0.35) | ACHE | |
| SCHEMBL1883074 | 0.81 | ACHE (0.35) | ACHE | |
| SCHEMBL18676835 | 0.80 | ACHE (0.66) | ACHEEPHX1 | |
| SCHEMBL1881136 | 0.80 | ACHE (0.37) | ACHE | |
| SCHEMBL18697924 | 0.80 | ACHE (0.70) | ACHEEPHX1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | SHIONOGI & CO., LTD. | 2012-08-16 | — | — | US | disclosed |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | SHIONOGI & CO. LTD. (JP) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208813-A1 | 3-CARBAMOYL-2-PYRIDONE DERIVATIVES | CNR2, CNR1, HRH4 | ACHE 611/4885EPHX1 1087/4885ALOX15 1008/4885 |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | CNR1, CNR2, HRH4 | ACHE 762/4885EPHX1 1472/4885ALOX15 767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.