Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11923074 | 1.00 | BCHE (0.41) | BCHEMAPTPRKAA1PRSS1TPSG1 | |
| SCHEMBL13574486 | 0.82 | BCHE (0.39) | BCHEPRSS1TPSG1 | |
| SCHEMBL637595 | 0.81 | MAPT (0.59) | BCHEMAPTPRKAA1PRSS1TPSG1 | |
| SCHEMBL637594 | 0.81 | MAPT (0.59) | BCHEMAPTPRKAA1PRSS1TPSG1 | |
| SCHEMBL12829089 | 0.80 | BCHE (0.39) | BCHEPRSS1TPSG1 | |
| SCHEMBL10195654 | 0.74 | CYP1A2 (0.45) | BCHE | |
| SCHEMBL12846700 | 0.72 | THRB (0.54) | BCHEMAPTTHRBLMNA | |
| SCHEMBL11888123 | 0.72 | THRB (0.54) | BCHEMAPTTHRBLMNA | |
| SCHEMBL12872554 | 0.72 | THRB (0.54) | BCHEMAPTTHRBLMNA | |
| SCHEMBL15890444 | 0.69 | MAPT (0.55) | BCHEMAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238143-B1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2012-08-15 | — | — | EP | disclosed |