Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.80 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278762 | 0.89 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL12292023 | 0.88 | TAS2R8 (0.84) | TAS2R8TAS2R14 | |
| SCHEMBL1279298 | 0.83 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278978 | 0.81 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL1279744 | 0.81 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278797 | 0.81 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL18351058 | 0.81 | TAS2R8 (0.87) | TAS2R8TAS2R14 | |
| SCHEMBL1279814 | 0.80 | TAS2R8 (1.00) | TAS2R8TAS2R14 | |
| SCHEMBL12062606 | 0.80 | TAS2R8 (0.83) | TAS2R8TAS2R14 | |
| SCHEMBL13940035 | 0.80 | TAS2R8 (0.85) | TAS2R8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-A1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | Senomyx Inc. (US) | 2012-08-15 | — | — | EP | disclosed |