Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12289315 | 0.95 | TAS2R8 (0.86) | TAS2R8 | |
| SCHEMBL1279039 | 0.93 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279090 | 0.88 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL12291999 | 0.86 | TAS2R8 (0.87) | TAS2R8 | |
| SCHEMBL12289821 | 0.84 | TAS2R8 (0.85) | TAS2R8 | |
| SCHEMBL11923500 | 0.84 | TAS2R8 (0.82) | TAS2R8 | |
| SCHEMBL13939296 | 0.83 | TAS2R8 (0.74) | TAS2R8 | |
| SCHEMBL1279296 | 0.82 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279300 | 0.82 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1279358 | 0.82 | TAS2R8 (1.00) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487169-A1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | Senomyx Inc. (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |