Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281575 | 0.86 | HPGD (0.69) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL19849385 | 0.84 | HPGD (0.63) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL14648456 | 0.77 | HPGD (0.68) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| Ciglitazone SCHEMBL38185 | 0.77 | HPGD (1.00) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| Ciglitazone SCHEMBL20125576 | 0.77 | HPGD (1.00) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| Ciglitazone SCHEMBL20125581 | 0.77 | HPGD (1.00) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL11925112 | 0.76 | HPGD (0.61) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| Ciglitazone SCHEMBL21582134 | 0.76 | HPGD (0.98) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| Ciglitazone SCHEMBL3189397 | 0.76 | HPGD (0.98) | HPGDMEN1ALDH1A1TP53CYP1A2 | |
| SCHEMBL11925114 | 0.75 | HPGD (0.60) | HPGDMEN1ALDH1A1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655314-B1 | MULTI-API LOADING PRODRUGS | ALKERMES PHARMA IRELAND LTD (IE) | 2018-02-07 | — | — | EP | disclosed |
| US-20160024011-A1 | Multi-API Loading Prodrugs | ALKERMES PHARMA IRELAND LTD (IE) | 2016-01-28 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120202823-A1 | Multi-API Loading Prodrugs | ALKERMES, INC. | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024011-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | HPGD 2055/4885MEN1 2927/4885ALDH1A1 525/4885 |
| US-20120202823-A1 | Multi-API Loading Prodrugs | AADAC, PAICS, ABCG2 | HPGD 2055/4885MEN1 2927/4885ALDH1A1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.