Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11925945 | 0.92 | GPR84 (0.41) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL14436820 | 0.78 | TET2 (0.56) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL4717704 | 0.78 | TET2 (0.56) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL995243 | 0.76 | TSHR (0.43) | TSHRKDM4AKDM4CKDM2ASLC1A1 | |
| SCHEMBL8943384 | 0.74 | GPR84 (0.45) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL8943387 | 0.74 | GPR84 (0.45) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL8943395 | 0.74 | GPR84 (0.45) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL3573769 | 0.73 | TSHR (0.54) | TSHRTET2KDM4AKDM4CKDM2A | |
| SCHEMBL8943253 | 0.72 | TET2 (0.46) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL8943261 | 0.72 | TET2 (0.46) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120207855-A1 | CEPHALOTAXINE ALKALOID COMPOSITIONS AND USES THEREOF | CHEMGENEX PHARMACEUTICALS, INC. (US) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120207855-A1 | CEPHALOTAXINE ALKALOID COMPOSITIONS AND USES THEREOF | TYMP, TOP2A, MTAP | TSHR 4536/4885TET2 237/4885KDM4A 1288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.